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        學術中心感染病學

        治愈乙肝新希望:親環素抑制劑

        ContraVir是一家專注于開發靶向抗病毒療法的生物制藥公司,尤其是抗乙肝病毒相關藥物的開發,其核心抗HBV藥物之一TXL(tenofovir exalidex,CMX157)是替諾福韋的脂質前藥,利用天然脂質攝取途徑將藥物送至肝臟,以減少替諾福韋的全身暴露劑量,從而降低腎臟和骨骼不良反應,目前處于IIa期階段。ContraVir另一款抗HBV藥物CRV431是新一代的親環素抑制劑,擁有特殊的結...

        Published 2017-4-18
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